CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way
DOI 10.1055/s-0033-1360940
Bibliografische Angaben
Nachweis in CareLit
Autor:innenW Stremmel, S Staffer, A Wannhoff, A Pathil-Warth, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Excess fat accumulation within the liver leads to non-alcoholic steatohepatitis (NASH)-a serious health threat worldwide. However, the responsible mechanisms and regulation of fatty acid uptake by hepatocytes remain to be uncovered. Using the hepatocyte-derived tumor cell line HepG2, we report that fatty acid influx is mediated by a specific (heterotetrameric) plasma membrane-protein complex constituted of FABPPM, c…
Zitieren
Zitierempfehlung
W Stremmel, S Staffer, A Wannhoff, A Pathil-Warth, W Chamulitrat (2014) Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360940
Mit CareLit weiterarbeiten