CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes
DOI 10.1055/s-0033-1360951
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Dauch, T Wuestefeld, TW Kang, R Rudalska, JC Nault, A Hohmeyer, L Hoenicke, P Schirmacher, T Longerich, J Zucman-Rossi, L Zender
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The tumor suppressor protein p19Arf (p14 in human) induces activation of p53 upon oncogenic stress. However, other functions of p19Arf, which are independent of p53 are also under discussion. To identify new tumor suppressive networks of p19Arf in hepatocellular carcinoma (HCC), we established a new mosaic liver cancer mouse model, based on the delivery of oncogenes and marker genes in combination with shRNAmir indu…
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Zitierempfehlung
D Dauch, T Wuestefeld, TW Kang, R Rudalska, JC Nault, A Hohmeyer, L Hoenicke, P Schirmacher, T Longerich, J Zucman-Rossi, L Zender (2014) A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360951
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