CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice
DOI 10.1055/s-0033-1360956
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Autor:innenHM Zimmermann, N Moro, R Sonntag, JM Bangen, YA Nevzorova, U Haas, D Lambertz, N Gassler, C Trautwein, C Liedtke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Caspase-8 (Casp8) is the apical protease essential for the initiation of extrinsic apoptosis. A role of Casp8 for preventing Hepatocellular Carcinoma (HCC) has been postulated. However, several studies revealed tumor suppressive, but also tumor promoting properties of Casp8 depending on the tissue environment. Therefore, the aim of this study was to investigate if Casp8 inhibits HCC-development in…
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Zitierempfehlung
HM Zimmermann, N Moro, R Sonntag, JM Bangen, YA Nevzorova, U Haas, D Lambertz, N Gassler, C Trautwein, C Liedtke (2014) Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360956
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