CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses
DOI 10.1055/s-0033-1360959
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Autor:innenD Ostroumov, MP Manns, S Kubicka, F Kühnel, T Wirth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Immunotherapy against liver cancer is a promising approach that needs to be further developed for the CD8 T cells. We have established an orthotopic HCC mouse model in order to study the influence of hepatocellular carcinoma on cytotoxic CD8 T cells. Hepatic tumors were generated in vivo using the "Sleeping beauty" transposon system. The transfection of murine hepatocytes with the plasmids that contain cDNA coding f…
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Zitierempfehlung
D Ostroumov, MP Manns, S Kubicka, F Kühnel, T Wirth (2014) Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360959
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