CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib
DOI 10.1055/s-0033-1360984
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Nachweis in CareLit
Autor:innenR Rudalska, D Dauch, K McJunkin, TW Kang, T Wuestefeld, R Geffers, P Schirmacher, S Lowe, T Longerich, S Laufer, L Zender
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocellular carcinoma represents the third common cause of cancer death and the incidence is steadily increasing. Standard treatments are limited due to frequent tumor recurrence and a poor responsiveness to conventional chemotherapy. The approval of sorafenib, a small multikinase inhibitor as the first active systemic treatment against HCC, increases survival of HCC patients by less than 3 months. Thus, there is…
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Zitierempfehlung
R Rudalska, D Dauch, K McJunkin, TW Kang, T Wuestefeld, R Geffers, P Schirmacher, S Lowe, T Longerich, S Laufer, L Zender (2014) Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360984
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