CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer
DOI 10.1055/s-0033-1360986
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Nachweis in CareLit
Autor:innenM Pesic, K Wolter, T Wuestefeld, TW Kang, R Chawla, R Geffers, F Klawonn, P Schirmacher, N Malek, PK Premsrirut, T Longerich, L Zender
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Due to the lack of treatment options hepatocellular carcinoma (HCC) represents the third most frequent cause of cancer related death. The major obstacle in HCC treatment is resistance to conventional chemotherapy and it becomes clear that new treatment strategies are urgently needed. We devised a system to conduct negative selection in vivo RNAi screens to identify new therapeutic target genes in Ras driven murine l…
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Zitierempfehlung
M Pesic, K Wolter, T Wuestefeld, TW Kang, R Chawla, R Geffers, F Klawonn, P Schirmacher, N Malek, PK Premsrirut, T Longerich, L Zender (2014) Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360986
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