CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo
DOI 10.1055/s-0033-1360987
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Autor:innenP Bozko, M El Khatib, V Palagani, N Malek, L Wilkens, R Plentz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Cholangiocarcinoma (CC) is a cancer disease which is increasing worldwide. The Notch signalling pathway is involved in the development and progression of several malignancies. However, the role of this Notch signaling in the carcinogenesis of CC is still not fully explored. In our study, we investigated the effects of Notch inhibition by gamma -secretase inhibitor IX (GSI IX) in cultured human CC cell…
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Zitierempfehlung
P Bozko, M El Khatib, V Palagani, N Malek, L Wilkens, R Plentz (2014) Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360987
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