CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation
DOI 10.1055/s-0033-1360988
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Nachweis in CareLit
Autor:innenA Mahli, WE Thasler, M Müller, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Preoperative chemotherapy with irinotecan is associated with the development of chemotherapy-associated steatohepatitis (CASH). Epidemiological studies have shown that irinotecan-treated obese patients have a higher risk to develop CASH and subsequent related mortality. However, the underlying mechanisms of these aggravated effects of irinotecan in hepatic steatosis are still unknown. The aim of this study was to es…
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Zitierempfehlung
A Mahli, WE Thasler, M Müller, C Hellerbrand (2014) Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360988
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