CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis
DOI 10.1055/s-0033-1360998
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Autor:innenJ Samarin, I Stein, E Horwitz, C Ho, X Chen, E Pikarsky, D Calvisi, P Schirmacher, K Breuhahn
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Far upstream element-binding proteins (FBPs) represent a family of transcription factors, which are highly overexpressed in the majority human hepatocellular carcinoma (HCC). Nuclear FBP accumulation in HCC cells support tumor cell proliferation (FBP-1/-3) and migration (FBP-3). Although, FBPs are promising therapeutic target structures, the underlying mode of dysregulation has not been defined so far. M…
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Zitierempfehlung
J Samarin, I Stein, E Horwitz, C Ho, X Chen, E Pikarsky, D Calvisi, P Schirmacher, K Breuhahn (2014) Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360998
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