CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins
DOI 10.1055/s-0033-1361007
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Schröder, Y Churin, M Roderfeld, D Glebe, E Roeb
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Chronic Hepatitis B (HBV) induces liver cirrhosis and liver cancer (HCC). The pathologic phenotype is based on host autoimmune reactions against the virus and by direct cytotoxic effects of viral components, e.g. the accumulation of the large surface protein of HBV (LHBs) in the endoplasmic reticulum (ER) of hepatocytes, which leads to ER-stress. If the cells cannot normalize the state by activating of protecting me…
Zitieren
Zitierempfehlung
D Schröder, Y Churin, M Roderfeld, D Glebe, E Roeb (2014) Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361007
Mit CareLit weiterarbeiten