CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deletion of Formyl-peptide receptors lead to an increased inflammatory response and enhanced liver injury following a bacterial induced hepatitis
DOI 10.1055/s-0033-1361015
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Autor:innenA Giebeler, U Neumann, LO Brandenburg
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The Formyl-peptide-receptor 1 and the formyl-peptide-receptor 2 (FPR1 and FPR2) were identified as receptors with a different affinity for the pathogen-associated-molecular-pattern (PAMP) N-formylmethionyl-leucyl-phenylalanine (fMLF). The tripeptide fMLF is a component of the bacterial membrane. During apoptosis it is secreted by the mitochondria of eukaryotic cells. Furthermore FPR1 and 2 are describe…
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Zitierempfehlung
A Giebeler, U Neumann, LO Brandenburg (2014) Deletion of Formyl-peptide receptors lead to an increased inflammatory response and enhanced liver injury following a bacterial induced hepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361015
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