CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide
DOI 10.1055/s-0033-1361020
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Nachweis in CareLit
Autor:innenA Hoh, A Schuch, Y Ni, A Bertoletti, HE Blum, S Urban, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
It is well accepted that virus-specific CD8+ T cells play an important role in the pathogenesis and clearance of hepatitis B virus (HBV) infection. However, so far little is known about the relative contribution of cytolytic versus non-cytolytic effector mechanisms to the inhibition of viral replication due to the lack of suitable cell culture models. Recently, hepatoma cells transduced with the HBV entry receptor h…
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Zitierempfehlung
A Hoh, A Schuch, Y Ni, A Bertoletti, HE Blum, S Urban, R Thimme (2014) Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361020
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