CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression of myelin auto-antigens and myelin altered peptide ligands in the liver in EAE mice models
DOI 10.1055/s-0033-1361024
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Autor:innenW Dammermann, K van der Maaden, S Lüth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aim: Hepatic expression of an alternated peptide ligand (APL) of myelin basic protein (MBP) leads to protection from experimental autoimmune encephalomyelitis (EAE) in mice. EAE constitutes a mouse model for multiple sclerosis in which MBP is one of the major auto-antigens. Other auto-antigens are myelin oligodendrocyte glycoprotein (MOG) and proteolipid protein (PLP). The tolerance is mediated by MBP…
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Zitierempfehlung
W Dammermann, K van der Maaden, S Lüth (2014) Expression of myelin auto-antigens and myelin altered peptide ligands in the liver in EAE mice models. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361024
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