CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice
DOI 10.1055/s-0033-1361026
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Nachweis in CareLit
Autor:innenJ Kah, T Volz, M Lütgehetmann, AW Lohse, G Tiegs, G Sass, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Hepatis C Virus (HCV) infection is a leading cause of chronic hepatitis worldwide. Induction of the anti-apoptotic, anti-inflammatory and anti-oxidant enzyme heme oxygenase 1 (HO-1) or application of its heme degradation product biliverdin has been shown to interfere with HCV replication in vitro. Enhancement of host anti-oxidant enzymes, such as HO-1, may attenuate hepatocyte injury during chronic HCV i…
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Zitierempfehlung
J Kah, T Volz, M Lütgehetmann, AW Lohse, G Tiegs, G Sass, M Dandri (2014) Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361026
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