CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection
DOI 10.1055/s-0033-1361050
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Autor:innenJM Werner, E Serti, X Chepa-Lotrea, J Stoltzfus, G Ahlenstiel, JJ Feld, JT Liang, Y Rotman, B Rehermann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Ribavirin is an important component of interferon-based and direct antiviral treatment regimens of hepatitis C virus (HCV) infection. Immunomodulation, in particular improvement of the host interferon response, has been proposed as a mechanism of action. Natural killer (NK) cells are sensitive biomarkers for IFN-α/β receptor signaling, as NK cell cytotoxicity and IFN-γ production are regulated by STAT1- and STAT4-ph…
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Zitierempfehlung
JM Werner, E Serti, X Chepa-Lotrea, J Stoltzfus, G Ahlenstiel, JJ Feld, JT Liang, Y Rotman, B Rehermann (2014) Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361050
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