CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model
DOI 10.1055/s-0033-1361054
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Nachweis in CareLit
Autor:innenK Krebs, N Böttinger, LR Huang, M Chmielewski, S Arzberger, G Gasteiger, F Bohne, M Aichler, W Uckert, H Abken, M Heikenwälder, P Knolle, U Protzer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Current antivirals suppress HBV but do not clear the infection. For virus clearance strong effector T cell responses are needed, which are sparse in chronically infected individuals. Cell therapy using T cells redirected by HBV-specific receptors may clear HBV and help to prevent and treat HBV-associated liver cancer. We designed a chimeric antigen receptor (CAR) that is composed of a single chain…
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Zitierempfehlung
K Krebs, N Böttinger, LR Huang, M Chmielewski, S Arzberger, G Gasteiger, F Bohne, M Aichler, W Uckert, H Abken, M Heikenwälder, P Knolle, U Protzer (2014) T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361054
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