CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection
DOI 10.1055/s-0033-1361057
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Autor:innenC Ehlting, M Trilling, C Tiedje, A Zimmermann, VTK Le, M Gaestel, H Hengel, D Häussinger, JG Bode
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The anti-inflammatory cytokine IL-10 inhibits the activity of Th1 cells, NK cells and macrophages, which are required for optimal pathogen clearance, but also contribute to tissue damage during infection. Cytomegalovirus (CMV) infection induces the expression of IL-10 to limit immune cell activation and to suppress IFNγ induced MHC class II surface expression, thereby escaping anti-viral mechanisms and diminishing t…
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Zitierempfehlung
C Ehlting, M Trilling, C Tiedje, A Zimmermann, VTK Le, M Gaestel, H Hengel, D Häussinger, JG Bode (2014) The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361057
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