CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen
DOI 10.1055/s-0033-1361059
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Nachweis in CareLit
Autor:innenCI Real, R Broering, K Jahn-Hofmann, L Ickenstein, M John, K Kleinehr, S Driftmann, T Kemper, HP Vornlocher, R Schirmbeck, M Lu, G Gerken, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Chronic infection with the hepatitis B virus (HBV) is a major cause of liver-related morbidity and mortality world-wide. Previously, it has been shown that toll-like receptor (TLR) signaling is impaired by HBsAg leading to an attenuation of innate and adaptive immune responses, which may possibly facilitate chronicity of infection. Here, we have studied TLR signaling in a HBV transgenic mouse model lac…
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Zitierempfehlung
CI Real, R Broering, K Jahn-Hofmann, L Ickenstein, M John, K Kleinehr, S Driftmann, T Kemper, HP Vornlocher, R Schirmbeck, M Lu, G Gerken, JF Schlaak (2014) Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1361059
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