CareLit · DOI-Nachweis · Zeitschrift für Geburtshilfe und Neonatologie
Genetic Low Nephron Number Hypertension is Associated with Altered Expression of the Renin-Angiotensin System (RAS) During Nephrogenesis
DOI 10.1055/s-0033-1361199
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Nachweis in CareLit
Autor:innenAL Freese, M Wehland, F Freese, R Kreutz, A Schulz, C Bamberg, L Rothermund
ZeitschriftZeitschrift für Geburtshilfe und Neonatologie
Ausgabe11/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Low nephron number may represent a major determinant of human primary hypertension in adult life. This hypothesis is supported by a genetic rat model, i.e., the Munich-Wistar Frömter (MWF) rat, which demonstrates an inherited deficit in nephron number and the development of spontaneous hypertension. The renin-angiotensin-system (RAS) plays a role in growth and differentiation processes during nephrogenesi…
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Zitierempfehlung
AL Freese, M Wehland, F Freese, R Kreutz, A Schulz, C Bamberg, L Rothermund (2013) Genetic Low Nephron Number Hypertension is Associated with Altered Expression of the Renin-Angiotensin System (RAS) During Nephrogenesis. Zeitschrift für Geburtshilfe und Neonatologie (11). https://doi.org/10.1055/s-0033-1361199
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