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Regulation of macroautophagy in amiodarone induced pulmonary fibrosis

P Mahavadi, I Henneke, L Knudsen, C Ruppert, S Venkatesan, G Liebisch, RC Chambers, K Piskulak, M Ochs, G Schmitz, C Vancheri, W Seeger, M Korfei, A Guenther · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0033-1363111

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Nachweis in CareLit

Autor:innenP Mahavadi, I Henneke, L Knudsen, C Ruppert, S Venkatesan, G Liebisch, RC Chambers, K Piskulak, M Ochs, G Schmitz, C Vancheri, W Seeger, M Korfei, A Guenther
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Rationale: Amiodarone (AD) is a well known anti arrhythmic drug, limited by its potential side effects. Severe pulmonary toxicity is reported in patients receiving amiodarone even at low doses, most common histological finding being chronic interstitial pneumonia. Amiodarone is known to induce autophagy in some cell types. A potential role for autophagy in the development of lung fibrosis has not been elucidated so…

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Zitierempfehlung

P Mahavadi, I Henneke, L Knudsen, C Ruppert, S Venkatesan, G Liebisch, RC Chambers, K Piskulak, M Ochs, G Schmitz, C Vancheri, W Seeger, M Korfei, A Guenther (2014) Regulation of macroautophagy in amiodarone induced pulmonary fibrosis. Pneumologie (02). https://doi.org/10.1055/s-0033-1363111

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