CareLit · DOI-Nachweis · Pneumologie
BIM-EL Counter-regulation by BCL2-α Leads to Resistance development to Tyrosine Kinase Inhibitors in Lung Cancer
DOI 10.1055/s-0033-1363112
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Simasi, A Schubert, C Oelkrug, A Gillissen, K Nieber
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Tyrosine kinase inhibitors (TKI) are important therapeutic agents in the treatment of lung cancer. These drugs have been reported to inhibit cancer growth in a small population of patients. It has also been observed that patients develop resistance after exposure to the drugs. In this study we sought to establish the role of the BCL2 family proteins in resistance development to TKI. It has been reporte…
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Zitierempfehlung
J Simasi, A Schubert, C Oelkrug, A Gillissen, K Nieber (2014) BIM-EL Counter-regulation by BCL2-α Leads to Resistance development to Tyrosine Kinase Inhibitors in Lung Cancer. Pneumologie (02). https://doi.org/10.1055/s-0033-1363112
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