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The innate immune response to Streptococcus pneumoniae in the lung is influenced by immunoproteasomes

F Kirschner, K Reppe, M Witzenrath, U Seifert, PM Kloetzel · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0033-1363125

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Autor:innenF Kirschner, K Reppe, M Witzenrath, U Seifert, PM Kloetzel
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The ubiquitin-proteasome system is responsible for degradation of most intracellular proteins and consists of two steps: ubiquitination and proteasome-mediated degradation. The proteasome is a large protease composed of multiple subunits that is present in all eukaryotic cells and is essential for many basic cellular processes such as protein homeostasis, cell growth and antigen presentation. Following infection and…

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F Kirschner, K Reppe, M Witzenrath, U Seifert, PM Kloetzel (2014) The innate immune response to Streptococcus pneumoniae in the lung is influenced by immunoproteasomes. Pneumologie (02). https://doi.org/10.1055/s-0033-1363125

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