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Chronic and chronic intermittent hypobaric hypoxia in rats leads to a mismatch in the endothelial ADMA/NO pathway

N Lueneburg, P Siques, J Brito, E Pena, K Arriaza, H Klose, RH Böger · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0034-1367746

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Autor:innenN Lueneburg, P Siques, J Brito, E Pena, K Arriaza, H Klose, RH Böger
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Hypoxia, either from altitude or clinical ailments is associated with pathophysiological conditions like mountain sickness and/or hypoxia-induced pulmonary hypertension. An endothelial dysfunction plays a crucial role in the manifestation of these diseases. Asymmetric dimethylarginine (ADMA) is an endogenous formed NO synthase (NOS) inhibitor and well known as a risk factor for respiratory diseases ass…

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N Lueneburg, P Siques, J Brito, E Pena, K Arriaza, H Klose, RH Böger (2014) Chronic and chronic intermittent hypobaric hypoxia in rats leads to a mismatch in the endothelial ADMA/NO pathway. Pneumologie (02). https://doi.org/10.1055/s-0034-1367746

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