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The role of CCR2+ CD4 T cells in lung fibrosis

K Milger, Y Yu, E Brudy, M Irmler, A Skapenko, M Mayinger, M Königshoff, O Eickelberg, S Krauss-Etschmann · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0034-1367779

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Autor:innenK Milger, Y Yu, E Brudy, M Irmler, A Skapenko, M Mayinger, M Königshoff, O Eickelberg, S Krauss-Etschmann
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: T cells have been suggested to play important roles in the development of lung fibrosis. Chemokine receptor 2 (CCR2), the receptor of macrophage chemoattractant protein-1 (MCP-1), is expressed by many immune cell types including T cells. The broad inhibition of CCR2-dependent signaling was shown to attenuate the development of pulmonary fibrosis in animal models. However, the specific role of CCR2+CD4+…

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Zitierempfehlung

K Milger, Y Yu, E Brudy, M Irmler, A Skapenko, M Mayinger, M Königshoff, O Eickelberg, S Krauss-Etschmann (2014) The role of CCR2+ CD4 T cells in lung fibrosis. Pneumologie (02). https://doi.org/10.1055/s-0034-1367779

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