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Polarized secreted IL-17C is a mediator of respiratory epithelial innate immune response

C Schmidt, M Voss, P Pfeifer, B Wonnenberg, F Langer, R Bals, C Beisswenger · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0034-1367783

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Autor:innenC Schmidt, M Voss, P Pfeifer, B Wonnenberg, F Langer, R Bals, C Beisswenger
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The IL-17 family of cytokines consists of at least six members (IL-17A to -F). IL-17 directly activates epithelial cells leading to the expression of inflammatory mediators and antimicrobial factors. In this study, our aim was to examine the expression and function of IL-17C in respiratory epithelial cells during bacterial infection. In vitro studies showed that common bacterial pathogens, such as Pseudomonas aerugi…

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Zitierempfehlung

C Schmidt, M Voss, P Pfeifer, B Wonnenberg, F Langer, R Bals, C Beisswenger (2014) Polarized secreted IL-17C is a mediator of respiratory epithelial innate immune response. Pneumologie (02). https://doi.org/10.1055/s-0034-1367783

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