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Treatment of allergic airway inflammation and airway hyperresponsiveness using RORγt specific RNAi

S Webering, L Lunding, H Fehrenbach, M Wegmann · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0034-1367907

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Autor:innenS Webering, L Lunding, H Fehrenbach, M Wegmann
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Recent studies suggest T helper 17 (TH17) cells as important players in the progression of asthma towards a severe phenotype. Characterized by the production of pro-inflammatory cytokines like TNF-α, IL-1ß, IL-22 and IL-17A, TH17 cells appear to act as general promoters of chronic inflammatory responses. These effector functions are initiated by the transcription factor Retinoic acid-related Orphan Rec…

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S Webering, L Lunding, H Fehrenbach, M Wegmann (2014) Treatment of allergic airway inflammation and airway hyperresponsiveness using RORγt specific RNAi. Pneumologie (02). https://doi.org/10.1055/s-0034-1367907

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