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Incidence of EGFR, KRAS, BRAF, ALK, and p53 alterations in a cohort of 161 consecutively tested patients from a certified lung cancer center, correlation with clinical characteristics and treatment outcome

A Lüers, V Halbfass, R Prenzel, D Scriba, KC Willborn, M Falk, C Hallas, M Tiemann, F Griesinger · Pneumologie · Ausgabe 02/2014

DOI 10.1055/s-0034-1367988

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Autor:innenA Lüers, V Halbfass, R Prenzel, D Scriba, KC Willborn, M Falk, C Hallas, M Tiemann, F Griesinger
ZeitschriftPneumologie
Ausgabe02/2014
Jahrgang / SeitenNicht angegeben

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Introduction: The aim of the study was to systematically analyze EGFR, KRAS, BRAF, ALK and p53 within the same cohort of patients, to correlate alterations with clinical characteristics and to potentially identify new prognostic/predictive markers. Methods: 161 patients from a single center diagnosed with lung cancer were studied for the presence of EGFR mutations, ALK rearrangements, KRAS codon 12/13/61 and BRAF V6…

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A Lüers, V Halbfass, R Prenzel, D Scriba, KC Willborn, M Falk, C Hallas, M Tiemann, F Griesinger (2014) Incidence of EGFR, KRAS, BRAF, ALK, and p53 alterations in a cohort of 161 consecutively tested patients from a certified lung cancer center, correlation with clinical characteristics and treatment outcome. Pneumologie (02). https://doi.org/10.1055/s-0034-1367988

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