CareLit · DOI-Nachweis · Klinische Pädiatrie
Identification of Endogenous Retrovirus Sequences that are Associated with Hodgkin's Lymphoma Specific Gene Expression
DOI 10.1055/s-0034-1371100
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Nachweis in CareLit
Autor:innenMS Staege, K Kruse, L Kielholz, MM Ruch, N Wappler, I Volkmer, S Kewitz, I Große
ZeitschriftKlinische Pädiatrie
Ausgabe03/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Question: Human endogenous retroviruses (ERV) represent approximately 10% of our DNA. The majority of these ERV loci are inactivated by mutations that disrupt open reading frames of the viral gag, pol, and env proteins. In addition, expression of most ERV elements is stringently shut off by epigenetic mechanisms. Reactivation of ERV expression has been observed in several diseases, ranging from cancer to neurodegene…
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Zitierempfehlung
MS Staege, K Kruse, L Kielholz, MM Ruch, N Wappler, I Volkmer, S Kewitz, I Große (2014) Identification of Endogenous Retrovirus Sequences that are Associated with Hodgkin's Lymphoma Specific Gene Expression. Klinische Pädiatrie (03). https://doi.org/10.1055/s-0034-1371100
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