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Combined Linkage and Association Studies of Antibodies against EBV Antigens Confirm the Role of HLA Class II Variants in the Control of Anti-EBNA1 IgG Levels and in the Risk of Hodgkin's Lymphoma

V Pedergnana, L Syx, A Cobat, J Guergnon, P Brice, C Ferme, P Carde, O Hermine, C Le Pendeven, C Amiel, I Theodorou, L Abel, C Besson · Klinische Pädiatrie · Ausgabe 03/2014

DOI 10.1055/s-0034-1371107

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Autor:innenV Pedergnana, L Syx, A Cobat, J Guergnon, P Brice, C Ferme, P Carde, O Hermine, C Le Pendeven, C Amiel, I Theodorou, L Abel, C Besson
ZeitschriftKlinische Pädiatrie
Ausgabe03/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

An altered anti-EBV serologic profile is associated with an increased risk of Hodgkin's lymphoma (HL) and has been shown to precede HL diagnosis. Recent studies have provided evidence for the role of genetic factors controlling both anti- viral capsid antigen (VCA) and anti- Epstein-Barr nuclear antigen-1 (EBNA-1) immunoglobulin (Ig)G levels. Here, we conducted linkage and association studies to further search for g…

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Zitierempfehlung

V Pedergnana, L Syx, A Cobat, J Guergnon, P Brice, C Ferme, P Carde, O Hermine, C Le Pendeven, C Amiel, I Theodorou, L Abel, C Besson (2014) Combined Linkage and Association Studies of Antibodies against EBV Antigens Confirm the Role of HLA Class II Variants in the Control of Anti-EBNA1 IgG Levels and in the Risk of Hodgkin's Lymphoma. Klinische Pädiatrie (03). https://doi.org/10.1055/s-0034-1371107

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