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Genetic Variants of Interleukin 10 (IL10) are Associated with Clinical Outcome and Tumor Microenvironment Composition of Classical Hodgkin Lymphoma (cHL)

M Vera-Lozada, M Barros, A García Costa, R Hassan · Klinische Pädiatrie · Ausgabe 03/2014

DOI 10.1055/s-0034-1371111

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Autor:innenM Vera-Lozada, M Barros, A García Costa, R Hassan
ZeitschriftKlinische Pädiatrie
Ausgabe03/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

IL10 is a immunoregulatory cytokine which expression is regulated mainly by promoter polymorphisms, which have previously been associated with prognosis in adult cHL. However, their effects on the outcome of pediatric patients remains unproven, as well as a model for the genetic control of IL10 expression, and its role in shaping the tumor microenvironment (TME). We analyzed IL10 polymorphisms in respect of therapy…

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M Vera-Lozada, M Barros, A García Costa, R Hassan (2014) Genetic Variants of Interleukin 10 (IL10) are Associated with Clinical Outcome and Tumor Microenvironment Composition of Classical Hodgkin Lymphoma (cHL). Klinische Pädiatrie (03). https://doi.org/10.1055/s-0034-1371111

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