CareLit · DOI-Nachweis · Klinische Pädiatrie
Prognostic impact of FLT3 gene expression and mutational status in pediatric MLL-rearranged ALL
DOI 10.1055/s-0034-1374824
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Fedders, M Zimmermann, G Cario, A Möricke, M Schrappe, M Stanulla
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
MLL-rearranged acute lymphoblastic leukemias (ALLs) are characterized by high levels of FLT3 gene expression. In addition, activating FLT3 mutations have been reported to be frequent secondary genetic events. However, the prognostic impact of both FLT3 gene expression and its mutational status remains controversial within this cytogenetic subgroup. We analyzed the presence of FLT3-internal tandem duplication (ITD) a…
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Zitierempfehlung
H Fedders, M Zimmermann, G Cario, A Möricke, M Schrappe, M Stanulla (2014) Prognostic impact of FLT3 gene expression and mutational status in pediatric MLL-rearranged ALL. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374824
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