CareLit · DOI-Nachweis · Klinische Pädiatrie
Regulating the activity of p38α/β as a potential therapy against childhood acute lymphoblastic leukemia
DOI 10.1055/s-0034-1374829
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Nachweis in CareLit
Autor:innenA Alsadeq, S Strube, S Krause, M Carlet, I Jeremias, C Vokuhl, S Loges, JA Aguirre-Ghiso, G Cario, M Stanulla, M Schrappe, DM Schewe
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Acute lymphoblastic leukemia (ALL) is the most common cancer in children, and 15% of the treated patients suffer from relapse. Understanding the biological factors that enhance or inhibit ALL cell proliferation can help in improving the current therapies. During normal hematopoiesis, the MAPK family member p38 mediates growth-inhibitory signals. In this study we have further investigated the role of p38 in ALL biolo…
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Zitierempfehlung
A Alsadeq, S Strube, S Krause, M Carlet, I Jeremias, C Vokuhl, S Loges, JA Aguirre-Ghiso, G Cario, M Stanulla, M Schrappe, DM Schewe (2014) Regulating the activity of p38α/β as a potential therapy against childhood acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374829
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