CareLit · DOI-Nachweis · Klinische Pädiatrie
Concurrent deIetions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 (IKZF1plus) confer a very poor prognosis in pediatric acute lymphoblastic leukemia
DOI 10.1055/s-0034-1374831
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Dagdan, M Zaliova, M Zimmermann, P Dörge, A Möricke, A Teigler-Schlegel, R Koehler, CR Bartram, J Alten, D Schewe, C Kratz, RS Houlston, M Schrappe, G Cario, M Stanulla
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Recently, we described GATA3 (rs3824662) as a new susceptibility locus for pediatric acute lymphoblastic leukemia (ALL; Blood;122:3298 – 3307). The variant GATA3 allele was specifically associated with so-called B-other ALL and conferred a dismal outcome. Here, we analyzed in 500 patients treated on trial AIEOP-BFM 2000 which somatic genetic aberrations describe the group of B-other ALLs associated with rs3824662 to…
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Zitierempfehlung
E Dagdan, M Zaliova, M Zimmermann, P Dörge, A Möricke, A Teigler-Schlegel, R Koehler, CR Bartram, J Alten, D Schewe, C Kratz, RS Houlston, M Schrappe, G Cario, M Stanulla (2014) Concurrent deIetions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 (IKZF1plus) confer a very poor prognosis in pediatric acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374831
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