CareLit · DOI-Nachweis · Klinische Pädiatrie
Darwinian Evolution of Acute Lymphoblastic Leukaemia
DOI 10.1055/s-0034-1374832
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Nachweis in CareLit
Autor:innenK Dormon, O Heidenreich
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Overall survival for paediatric ALL is favourable, but after relapse this rate drops dramatically. Many patients who relapse will have an aggressive drug resistant disease, clonally evolved from a presentation or ancestral clone, acquiring mutations in a Darwinian manner. We previously characterised a presentation/relapse pair derived from a t(17;19) pre B ALL patient sample in which the relapse has a 5q deletion sp…
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Zitierempfehlung
K Dormon, O Heidenreich (2014) Darwinian Evolution of Acute Lymphoblastic Leukaemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374832
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