CareLit · DOI-Nachweis · Klinische Pädiatrie
A caspase gene-based security mechanism for potential leukemogenesis in human cord blood-derived T cell progenitors
DOI 10.1055/s-0034-1374839
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Hübner, S Hoseini, M Hapke, J Herbst, J Sürth, H Maul, A Schambach, M Brenner, M vd Brink, M Sauer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
* these authors contributed equally. Co-transplantation of genetically engineered T cell precursors together with hematopoietic stem cells is a promising means of specifically target tumor-associated antigens but avoid non specific alloreactivity causing graft versus host disease complicating the adoptive transfer of allogeneic mature T cells. However, genetic modification of undifferentiated precursor cells bears t…
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Zitierempfehlung
J Hübner, S Hoseini, M Hapke, J Herbst, J Sürth, H Maul, A Schambach, M Brenner, M vd Brink, M Sauer (2014) A caspase gene-based security mechanism for potential leukemogenesis in human cord blood-derived T cell progenitors. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374839
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