CareLit · DOI-Nachweis · Klinische Pädiatrie
Fibroblast growth factor receptors as therapeutic targets in neuroblastoma
DOI 10.1055/s-0034-1374843
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Arnz, F Hertwig, A Krämer, F Ikram, F Roels, H Kocak, A Engesser, R Thomas, M Peifer, S Ackermann, M Fischer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
To identify progression-driving molecular alterations in neuroblastoma, we used DNA deep-sequencing of 213 primary tumors, RNA deep-sequencing of 498 primary tumors, and microarray gene expression analysis of 709 tumors. While a heterogeneous mutation spectrum was observed in general, we identified putatively activating mutations in fibroblast growth factor receptor (FGFR) tyrosine kinase genes in several cases of h…
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Zitierempfehlung
E Arnz, F Hertwig, A Krämer, F Ikram, F Roels, H Kocak, A Engesser, R Thomas, M Peifer, S Ackermann, M Fischer (2014) Fibroblast growth factor receptors as therapeutic targets in neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374843
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