CareLit · DOI-Nachweis · Klinische Pädiatrie
Signatures of Mutational Processes in Childhood Cancers
DOI 10.1055/s-0034-1374847
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSN Groebner, M Zapatka, RM Piro, SM Pfister
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Backgrounds: Most cancers arise as consequence of the accumulation of somatic mutations, including specific driver mutations and random passenger mutations. Both represent the imprint of different DNA damage and DNA repair processes interfering with the genome, which can also be referred to as mutational signatures. Methods: Recently, a method deciphering mutational signatures by modelling the underlying processes a…
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Zitierempfehlung
SN Groebner, M Zapatka, RM Piro, SM Pfister (2014) Signatures of Mutational Processes in Childhood Cancers. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374847
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