CareLit · DOI-Nachweis · Klinische Pädiatrie
CD57high neuroblastoma cells have aggressive attributes ex situ and an undifferentiated phenotype in patients
DOI 10.1055/s-0034-1374851
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Nachweis in CareLit
Autor:innenAM Schlitter, C Dorneburg, TFE Barth, J Wahl, JH Schulte, S Brüderlein, KM Debatin, C Beltinger
ZeitschriftKlinische Pädiatrie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Neuroblastoma is thought to originate from neural crest-derived cells. CD57 defines migratory neural crest cells in normal development and is expressed in neuroblastoma. Methods: We investigated the role of CD57 expression in neuroblastoma cells ex situ and in situ. Results: Compared to CD57low U-NB1 neuroblastoma cells, CD57high cells developed tumors with decreased latency after orthotopic transplant…
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Zitierempfehlung
AM Schlitter, C Dorneburg, TFE Barth, J Wahl, JH Schulte, S Brüderlein, KM Debatin, C Beltinger (2014) CD57high neuroblastoma cells have aggressive attributes ex situ and an undifferentiated phenotype in patients. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0034-1374851
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