CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Adipose-tissue specific knockout of ERalpha using the aP2-Cre induces fatal effects on the reproductive tract of female mice
DOI 10.1055/s-0034-1374878
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Nachweis in CareLit
Autor:innenV Benz, Z Bán, L Mundhenk, G Schuler, S Brix, J Grune, A Foryst-Ludwig, U Kintscher
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Estrogens (E2) via estrogen receptors (ER) are known to influence energy expenditure and adipose tissue (AT) metabolism via central and peripheral effects. To investigate primarily peripheral effects of E2, female AT-specific (ap2-Cre) ERα-floxed knockout (KO) mice and their control littermates (WT) were fed a high-fat diet (HFD) for 15 weeks. Metabolic phenotyping and gene-expression analysis were performed before…
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Zitierempfehlung
V Benz, Z Bán, L Mundhenk, G Schuler, S Brix, J Grune, A Foryst-Ludwig, U Kintscher (2014) Adipose-tissue specific knockout of ERalpha using the aP2-Cre induces fatal effects on the reproductive tract of female mice. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374878
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