CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Stepwise reprogramming of liver to pancreas under the control of a single transcriptional regulator
DOI 10.1055/s-0034-1374888
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Autor:innenN Cerdá-Esteban, A Hommel, E Bonifacio, FM Spagnoli
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Reprogramming of somatic cells into pancreatic beta-cells represents a promising strategy for cell-based therapy of diabetes. The liver is an ideal tissue source for generating new beta-cells, due to its close developmental origin with the pancreas and its regenerative ability. However, the molecular basis of hepatic and pancreatic cellular plasticity is still poorly understood. We have identified the TALE homeodoma…
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Zitierempfehlung
N Cerdá-Esteban, A Hommel, E Bonifacio, FM Spagnoli (2014) Stepwise reprogramming of liver to pancreas under the control of a single transcriptional regulator. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374888
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