CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
CD40-TRAF6 pathway as a therapeutic target in obesity-associated metabolic dysfunction
DOI 10.1055/s-0034-1374895
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Autor:innenA Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, KJ Chung, R Garcia Martin, E Lutgens, T Triantafyllos
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: Inflammation contributes to the pathogenesis of obesity-associated metabolic dysregulation and co-stimulatory molecules, including CD40, are important mediators of this process. This study aimed to reveal the role of CD40 and its signaling intermediates, TNF-Receptor-Associated-Factors (TRAFs), in diet-induced obesity (DIO). Methods: The DIO model was performed in CD40-deficient or -sufficient mice as wel…
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Zitierempfehlung
A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, KJ Chung, R Garcia Martin, E Lutgens, T Triantafyllos (2014) CD40-TRAF6 pathway as a therapeutic target in obesity-associated metabolic dysfunction. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374895
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