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Innate immune responses and type 1 diabetes: A role for a long non-coding RNA?

MP Ashton, I Tan, L Mackin, C Elso, E Chu, A Papenfuss, B Phipson, G Smyth, M O'Keeffe, S Summers, N Payne, C Bernard, T Brodnicki · Diabetologie und Stoffwechsel · Ausgabe 05/2014

DOI 10.1055/s-0034-1374906

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Autor:innenMP Ashton, I Tan, L Mackin, C Elso, E Chu, A Papenfuss, B Phipson, G Smyth, M O'Keeffe, S Summers, N Payne, C Bernard, T Brodnicki
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Pattern recognition receptors (PRRs) act as early sensors of microbial pathogens, but accumulating evidence indicates that PRRs also play an important role in autoimmunity. In particular, manipulation of toll-like receptors (TLRs) in the non-obese diabetic (NOD) mouse strain alters the onset of type 1 diabetes (T1D). We have identified a novel gene (Apics), for which sequence variation is associated wi…

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Zitierempfehlung

MP Ashton, I Tan, L Mackin, C Elso, E Chu, A Papenfuss, B Phipson, G Smyth, M O'Keeffe, S Summers, N Payne, C Bernard, T Brodnicki (2014) Innate immune responses and type 1 diabetes: A role for a long non-coding RNA?. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374906

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