CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Phenotypic characterization of HLA-DQ8-restricted insulin-specific CD4+ T cells in longterm-autoantibody positive children
DOI 10.1055/s-0034-1374907
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Nachweis in CareLit
Autor:innenI Serr, F Gökmen, R Willis, AG Ziegler, C Daniel
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Scientific question: The appearance of multiple islet-autoantibodies in children denotes a point of limited return in the immunepathogenesis of Type 1 Diabetes. However, once islet autoimmunity is established the time frame to overt diabetes is variable ranging from several months to more than two decades. We ask whether such longterm non-progressors will help to identify states of ongoing immune activation vs. regu…
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Zitierempfehlung
I Serr, F Gökmen, R Willis, AG Ziegler, C Daniel (2014) Phenotypic characterization of HLA-DQ8-restricted insulin-specific CD4+ T cells in longterm-autoantibody positive children. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374907
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