CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
In vivo kinetics of islet compensation and dysfunction in a mouse model of diet-induced obesity and insulin resistance
DOI 10.1055/s-0034-1374921
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Chen, JA Chouinard, CM Cohrs, S Speier
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Pancreatic islets have been shown to initially increase function and mass during the development of obesity and insulin resistance (IR), but to fail later under the metabolic pressure. However, the kinetics of transition from successful islet compensation to islet dysfunction is largely unknown. Here, we aimed to longitudinally assess the adaptation of islet cell mass and function during obesity induced IR in…
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Zitierempfehlung
C Chen, JA Chouinard, CM Cohrs, S Speier (2014) In vivo kinetics of islet compensation and dysfunction in a mouse model of diet-induced obesity and insulin resistance. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374921
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