CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Insulinotropic effect of high potassium concentration beyond plasma membrane depolarization
DOI 10.1055/s-0034-1374922
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Nachweis in CareLit
Autor:innenN Görgler, M Belz, M Willenborg, K Schumacher, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: In experiments designed to dissect the signalling pathways in beta cells, the depolarizing effect of glucose metabolism is often replaced by a strong K+ depolarization. Recent observations raised doubt that high K+ is an appropriate experimental substitute for the physiologically induced depolarization. Methods: Using mouse islets insulin secretion was measured by batch perifusion and ELISA and…
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Zitierempfehlung
N Görgler, M Belz, M Willenborg, K Schumacher, I Rustenbeck (2014) Insulinotropic effect of high potassium concentration beyond plasma membrane depolarization. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374922
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