CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Humoral factors by human bone marrow-derived MSC enhance beta cell proliferation via ERK1/2 signalling
DOI 10.1055/s-0034-1374923
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Liu, L Lang, AE Mehana, B Mihic-Necic, L Parsons, J Baumann, C Jäger, N Perakakis, K Laubner, J Seufert, G Päth
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aim: We previously demonstrated that human telomerase-immortalised MSC (hMSC-TERT) migrate towards injured rat INS-1E beta cells, promote their survival and reduce their apoptosis via p-AKT-Bcl2/Bax signalling pathway. Both cell lines are valid models since they closely resemble results from primary rat MSC and rat islets. Here, we further tested whether hMSC-TERT promote the proliferation and functio…
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Zitierempfehlung
C Liu, L Lang, AE Mehana, B Mihic-Necic, L Parsons, J Baumann, C Jäger, N Perakakis, K Laubner, J Seufert, G Päth (2014) Humoral factors by human bone marrow-derived MSC enhance beta cell proliferation via ERK1/2 signalling. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374923
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