CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Mast cell protease-4 mediates obesity-related metabolic dysregulation via negative effect on adiponectin levels
DOI 10.1055/s-0034-1374967
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Autor:innenJ Chmelar, A Chatzigeorgiou, T Chavakis
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: Mast cells were recently found as key players in obesity-related metabolic dysregulation. Our study addresses the role of mast cell protease-4 (mcpt4 – the mouse counterpart of human chymase) in obesity and insulin resistance development. Methods: Mcpt4 defficient mice (mcpt4-/-) and control mice were fed a high fat diet in diet-induced obesity (DIO) experiment or a normal diet. Mice were tested for gluc…
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Zitierempfehlung
J Chmelar, A Chatzigeorgiou, T Chavakis (2014) Mast cell protease-4 mediates obesity-related metabolic dysregulation via negative effect on adiponectin levels. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1374967
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