CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Methylglyoxal administration induces inflammatory response and microglial activation in the mouse retina
DOI 10.1055/s-0034-1375012
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Autor:innenJ Wang, J Lin, M Aras, M Kolibabka, L Kern, P Friedrichs, J Friedrichs, P Järgen, N Dietrich, T Fleming, HP Hammes
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Question: Methylglyoxal (MG) is a highly reactive glucose metabolite and modifies both protein and DNA leading to an upregulation of many inflammatory and tissue-injury-provoking molecules. It therefore has an important role in the development of diabetic complications such as diabetic retinopathy, whereas its exact role yet needs to be demonstrated. We determine which impact MG alone has on the inflammatory respons…
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Zitierempfehlung
J Wang, J Lin, M Aras, M Kolibabka, L Kern, P Friedrichs, J Friedrichs, P Järgen, N Dietrich, T Fleming, HP Hammes (2014) Methylglyoxal administration induces inflammatory response and microglial activation in the mouse retina. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375012
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