CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Activation of autoreactive CD4+ T cells is synchronous to islet autoantibody seroconversion and shows an IFNγ signature
DOI 10.1055/s-0034-1375044
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Kühn, AK Heninger, A Eugster, S Dietz, C Winkler, M Scholz, AG Ziegler, E Bonifacio
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Islet autoantibody seroconversion is the first detectable evidence of autoimmunity preceding type 1 diabetes. Autoantibodies are markers of pre-diabetes, but T cells mediate beta cell destruction. Little is known about the timing of autoreactive T cell activation against beta cell antigens in the prediabetic period. The BABYDIET study followed children with a strong genetic predisposition for type 1 diabetes with fr…
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Zitierempfehlung
D Kühn, AK Heninger, A Eugster, S Dietz, C Winkler, M Scholz, AG Ziegler, E Bonifacio (2014) Activation of autoreactive CD4+ T cells is synchronous to islet autoantibody seroconversion and shows an IFNγ signature. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375044
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