CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Establishment of an in vivo mouse model that can be induced to produce IL-7
DOI 10.1055/s-0034-1375046
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Nachweis in CareLit
Autor:innenA Hommel, M Weigelt, A Karasinsky, C Wilhelm, A Lindner, K Anastassiadis, E Bonifacio
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims/hypothesis: The IL-7 pathway plays an important role in the autoimmune T cell mediated islet beta-cell loss following islet transplantation in T1D, and may be a therapeutic target in cell replacement therapies. An experimental in vivo model to formally demonstrate this and to define the mechanisms involved, as well as strategies to prevent this process, is not available. Methods: Transgenic mice with a tetracyc…
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Zitierempfehlung
A Hommel, M Weigelt, A Karasinsky, C Wilhelm, A Lindner, K Anastassiadis, E Bonifacio (2014) Establishment of an in vivo mouse model that can be induced to produce IL-7. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375046
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